Here’s another question. Do you believe in predestination? Of course I do. How else could I believe when it says in Ephesians chapter 1 these wonderful words? And I thank God for these words, and you know them well. “According as He has chosen us in Him before the foundation of the world that we should be holy and without blame before Him.” Yes, He chose us before the foundation of the world, “In love, having predestinated us unto the adoption of sons by Jesus Christ to Himself, according to the good pleasure of our will.” Is that what it said? His will. Do I believe in predestination? What else could I believe? It’s in the Bible.
In Romans 9, He says, “Jacob have I loved, and Esau have I hated.” He says in that same passage there, “Are vessels fitted unto honor. There are vessels that have been fitted to destruction.” Yes, God is a sovereign God, but I believe also that somehow, mysteriously, within the framework of predestination and within the framework of His sovereignty and the framework of election, which I believe in, there is a place for human choice; and how that resolves itself is God’s problem. I’m gonna leave it with Him.
— John MacArthur, from Bible Questions and Answers Part 1